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61.
Fat mass is inversely associated with vitamin D status, and athletes with the most adipose tissue may have the greatest risk for insufficient (25(OH)D 20–32?ng?mL?1) or deficient (25(OH)D??1) status. The effects of fat and lean mass on 25(OH)D change in response to vitamin D supplementation have yet to be elucidated in athletes. In addition, vitamin D has a known role in bone health yet a link between short-term changes in 25(OH)D and bone turnover in indoor athletes have not yet been described. Thirty-two collegiate swimmers and divers (19 male, 13 female; 19 (1) years) participated in a 6-month randomized controlled trial and consumed either 4000?IU?d?1 of vitamin D3 (n?=?19) or placebo (PLA; n?=?13). Anthropometry and blood collection of 25(OH)D, bone-specific alkaline phosphatase (B-ALP) and N-terminal telopeptide (NTx) occurred at three time points. Dual-energy X-ray absorptiometry measured body composition analysis at baseline and endpoint. In the vitamin D group, BMI was negatively correlated with 6-month 25(OH)D change (R?=??0.496; P?=?.03) and a stronger predictor of 25(OH)D change (P?=?.04) than ultraviolet B exposure and fat mass change. Athletes in the high bone turnover group showed significantly greater losses of 25(OH)D over 6-months compared to athletes in the low bone turnover group (P?=?.03). These results suggest athletes within the normal BMI category experience a diminished response to 4000?IU?d?1 of vitamin D3 supplementation, and periods of high bone turnover may be an additional risk factor for developing compromised vitamin D status in athletes.  相似文献   
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X-linked adrenoleukodistrophy is a severe neurodegenerative disorder with impaired very long chain fatty acid metabolism. The disease associated ABCD1 gene encodes a peroxisomal membrane protein which belongs to the superfamily of ATP-binding cassette transporters. We investigated eight male X-ALD patients diagnosed among 142 suspected patients referred for investigation. Plasma levels of very long chain fatty acids were measured at our laboratory using capillary gas chromatography. Eight cases of childhood X-ALD were diagnosed. This is the first published series of Serbian patients with X-ALD. In addition, diagnosis identifies carriers, which could be benefit for genetic counselling and prenatal diagnosis.  相似文献   
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Design for a common world: On ethical agency and cognitive justice   总被引:1,自引:0,他引:1  
The paper discusses two answers to the question, How to address the harmful effects of technology? The first response proposes a complete separation of science from culture, religion, and ethics. The second response finds harm in the logic and method of science itself. The paper deploys a feminist technoscience approach to overcome these accounts of neutral or deterministic technological agency. In this technoscience perspective, agency is not an attribute of autonomous human users alone but enacted and performed in socio-material configurations of people and technology and their ‘intra-actions’. This understanding of agency is proposed as an alternative that opens up for the reconfiguration of design and use for more ethical effects, such as the cultivation of cognitive justice, the equal treatment and representation of different ways of knowing the world. The implication of this approach is that design becomes an adaptive and ongoing intra-active process in which more desirable configurations of people and technology become possible.  相似文献   
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This research study investigates co-ordination strategies within schools, their relationships to both teacher and student commitment to school, and the relationship between student commitment and student achievement in Switzerland. Two different kinds of co-ordination strategies, structural and cultural, can be distinguished. Structural co-ordination strategies have to do with formal, lasting arrangements that allow an organisation to operate. These include roles, rules, procedures, and authority relations. Cultural co-ordination strategies are related to the nature of communications and the consensus on organisational goals in the school. Cultural mechanisms shape what teachers want to do. Drawn from TIMSS, the sample for the present analyses included principals, teachers and students in 178 classes at the lower secondary level in three Swiss cantons: Bale-Country, Berne and Zurich. Multiple regression analyses carried out with different indicators of teacher and student commitment to school showed that school coordination strategies can make a difference, although the effects were rather small. A further analysis that included student commitment indicators as predictors of mathematics achievement suggests that the affective/social and the cognitive domains are relatively independent at class level.  相似文献   
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The aim of this study was to determine how parents select picture books for their children and which bibliographic data are important as they choose between different versions of the same title. Thirty-six parents of preschool children aged one to six years were interviewed and observed as they chose one version of the picture book Cinderella from among six bibliographic records and then selected from among six physical versions. Parents described the criteria and the reasons for their selections. The results indicate that the parents experienced difficulties using the library catalog and that the current bibliographic elements are inadequate.  相似文献   
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This paper reports on and draws conclusions about the international course called European Global Product Realization. It was organized to provide university students with knowledge about distributed product development in virtual enterprises. The philosophy of the course is discussed together with its structure, contents, organization, infrastructure, deliverables and the experiences. Necessitated by globalization, the principles of operation of virtual enterprises were used in organizing the course. The knowledge accumulated in global product realization by the participating companies and academic sections provided the basis for the course and for the student projects. The organizers put the students of three European universities into the position of evolving young professionals who act as both knowledge producers and knowledge consumers. The design and engineering students took part in academic lectures and industrial case studies in a virtual classroom and practised collaborative product development in the emulated virtual enterprise. The academic virtual enterprise framework has been confirmed to be a solution for opening the conventional educational institutions. Our future work will concentrate on how to exploit disciplinary and operational research as the engine behind academic learning and teaching.  相似文献   
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This exploratory qualitative study examined faculty responses to a collegiality-building process called Dialogues. The process used a series of discussions and activities to guide faculty members toward a common, mutually beneficially goal, while changing patterns of interaction. The responses revealed how faculty members experienced collegiality-building practices, including individual reflection, small group discussions, idea generation and prioritization, and consensus-building. The study examined faculty responses within STEM departments. We conclude with recommendations for encouraging inclusive and participatory departmental norms and behaviors in order to promote a positive departmental climate, which is crucial to achieving equity in all disciplines of the academia.  相似文献   
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Two studies were conducted in the US and Denmark to examine parents’ beliefs about the importance of play and nature experiences for early childhood development. Thirty parents in the US and 19 parents in Denmark completed semi-structured interviews with quantitative and qualitative elements. Although families in both contexts highly valued outdoor and nature experiences, parents in the Danish context provided a stronger rationale for taking children outdoors regardless of environmental conditions and affording them opportunities to explore freely and take risks. Parents in the US focused mainly on individual developmental benefits of play, whereas parents in Denmark also acknowledged the importance of spending time in nature for society and the environment. The findings provide evidence that sociocultural values and expectations influence parental beliefs and practices regarding outdoor and nature play, and have implications for young children’s play opportunities within and across cultural contexts.  相似文献   
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